Now showing items 31-40 of 70
Substitution of Moxifloxacin for Isoniazid during intensive phase treatment of Pulmonary Tuberculosis.
(American Thoracic Society., 2009)
Rationale: Moxifloxacin has potent activity against Mycobacterium tuberculosis in vitro and in a mouse model of antituberculosis (TB) chemotherapy, but data regarding its activity in humans are limited. Objectives: Our ...
Broad neutralization of human immunodeficiency virus type 1 mediated by plasma antibodies against the gp41 membrane proximal external region.
(American Society for Microbiology., 2009)
We identified three cross-neutralizing plasma samples with high-titer anti-membrane proximal external region (MPER) peptide binding antibodies from among 156 chronically human immunodeficiency virus type 1-infected ...
Commentary: Spatial clustering of HIV infection: providing clues for effective HIV prevention.
(Oxford University Press for the International Epidemiological Association., 2009)
No abstract available.
Human immunodeficiency virus-specific gamma interferon enzyme-linked immunospot assay responses targeting specific regions of the proteome during primary subtype C infection are poor predictors of the course of viremia and set point.
(American Society for Microbiology., 2008)
It is unknown whether patterns of human immunodeficiency virus (HIV)-specific T-cell responses during acute infection may influence the viral set point and the course of disease. We wished to establish whether the magnitude ...
Global epidemiology of HIV-AIDS.
(WB Saunders., 2007)
HIV, the cause of AIDS, has in the 25 years since its discovery spread rapidly to every region in the world . To date, more than 65 million people have been infected with HIV and about 25 million people have died ...
XDR-TB in South Africa : no time for denial or complacency.
On September 1, 2006, the World Health Organisation (WHO) announced that a deadly new strain of extensively drug-resistant tuberculosis (XDR-TB) had been detected in Tugela Ferry (Figure 1), a rural town in the South African ...
Grand challenges in global health : ethical, social, and cultural issues based on key informant perspectives.
The authors interviewed key informants from the developing world and the Grand Challenges investigators to explore their ethical, social, and cultural concerns about the program.
Establishing a cohort at high risk of HIV infection in South Africa: challenges and experiences of the CAPRISA 002 Acute Infection Study.
Objectives: To describe the baseline demographic data, clinical characteristics and HIV-incidence rates of a cohort at high risk for HIV infection in South Africa as well as the challenges experienced in establishing and ...
High treatment failure and default rates for patients with multidrug-resistant tuberculosis in KwaZulu-Natal, South Africa, 2000–2003.
(The Union., 2009)
SETTING: Multidrug-resistant tuberculosis (MDR-TB) has emerged as a significant public health threat in South Africa. OBJECTIVE: To describe treatment outcomes and determine risk factors associated with unfavorable outcomes ...
Grand challenges in global health : engaging civil society organizations in biomedical research in developing countries.
The authors discuss the different types of civil society organizations, their role in biomedical research, and the advantages and challenges of working with them.