Search
Now showing items 1-10 of 59
A reliable phenotype predictor for human immunodeficiency virus type 1 subtype C based on envelope V3 sequences.
(American Society for Microbiology., 2005)
In human immunodeficiency virus type 1 (HIV-1) subtype B infections, the emergence of viruses able to use
CXCR4 as a coreceptor is well documented and associated with accelerated CD4 decline and disease progression.
However, ...
Prospects for passive immunity to prevent HIV infection.
(Public Library of Science., 2017)
Abstract available in pdf.
Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization.
(American Association for the Advancement of Science., 2012)
Serum characterization and antibody isolation are transforming our understanding of the humoral immune response to viral infection. Here, we show that epitope specificities of HIV-1–neutralizing antibodies in serum can be ...
Sensitive tenofovir resistance screening of HIV-1 from the genital and blood compartments of women with breakthrough infections in the CAPRISA 004 tenofovir gel trial.
(Oxford University Press., 2014)
The Centre for the AIDS Programme of Research in South Africa 004 (CAPRISA 004) study demonstrated that vaginally applied tenofovir gel is a promising intervention for protecting women from sexually acquiring human ...
Immunoglobulin gene insertions and deletions in the affinity maturation of HIV-1 broadly reactive neutralizing antibodies.
(Cell Press., 2014)
Abstract available in pdf.
Rapid disease progression in HIV-1 subtype C–infected South African women.
(Oxford University Press., 2014)
Background. Whereas human immunodeficiency virus (HIV) subtype B–infected individuals generally progress to AIDS within 8–10 years, limited data exist for other clades, especially from Africa. We investigated rates of HIV ...
Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women.
(American Association for the Advancement of Science., 2010)
The Centre for the AIDS Program of Research in South Africa (CAPRISA) 004 trial assessed the effectiveness and safety of a 1% vaginal gel formulation of tenofovir, a nucleotide reverse transcriptase inhibitor, for the ...
Randomized cross-sectional study to compare HIV-1 specific antibody and cytokine concentrations in female genital secretions obtained by menstrual cup and cervicovaginal lavage.
(Public Library of Science., 2015)
Abstract available in pdf.
Establishing a cohort at high risk of HIV infection in South Africa: challenges and experiences of the CAPRISA 002 Acute Infection Study.
(Plos., 2007)
Objectives: To describe the baseline demographic data, clinical characteristics and HIV-incidence rates of a cohort at high
risk for HIV infection in South Africa as well as the challenges experienced in establishing and ...
Human immunodeficiency virus-specific gamma interferon enzyme-linked immunospot assay responses targeting specific regions of the proteome during primary subtype C infection are poor predictors of the course of viremia and set point.
(American Society for Microbiology., 2008)
It is unknown whether patterns of human immunodeficiency virus (HIV)-specific T-cell responses during acute infection may influence the viral set point and the course of disease. We wished to establish whether the magnitude ...