Doctoral Degrees (Clinical Medicine)
Recent Submissions
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Adequate analgesia in caring for paediatric burns patients in a peri-urban setting in KZN.
(2020)This PhD thesis centres on achieving adequate analgesia in caring for paediatric burn-injured patients in KwaZulu-Natal, South Africa. The burden of burn injuries in sub-Saharan Africa is huge. A large number of children ... -
Epidemiology of chronic kidney disease in KwaZulu-Natal: evaluation of risk factors, complications and diagnostic methods.
(2017)Chronic kidney disease (CKD) is associated with increased morbidity and mortality as well as costly renal replacement therapy. The aim was to determine risk factors and complications that contribute to morbidity as ... -
The use of feedback and feed-forward action plans on the development of clinical skills in undergraduate medical students.
(2019)Background: Deliberate practice is a concentrated learning strategy aimed at achieving a defined goal and feedback enables skills and behaviours to be corrected or reinforced for improved patient care. Clinical skills are ... -
Snakebite in KwaZulu-Natal: the burden of disease and prediction of risk of adverse outcomes.
(2016)BACKGROUND The total number of snakebites per annum in KwaZulu-Natal (KZN) is unknown. Yet it is believed that the burden that snakebites place on hospitals in areas with a high incidence of snakebite is significant. ... -
Acute pancreatitis in a high HIV prevalence environment: analysis of prevalence, demographics, prognosticators and outcomes.
(2019)Background It is unclear what is the true prevalence of HIV related acute pancreatitis and whether diagnostic and prognostic markers used in patients without HIV infection are as effective in HIV related pancreatitis and ... -
Radiologic evaluation of breast disorders related to tuberculosis amongst women in Durban, KwaZulu-Natal, South Africa.
(2016)Women in KwaZulu-Natal Province, South Africa, are at high risk of developing breast tuberculosis (BTB) due to the increased incidence of HIV. However, there is a general lack of knowledge regarding the various diseases ... -
The effect of HIV infection on the management of end-stage renal failure among patients undergoing continuous ambulatory peritoneal dialysis.
(2017)Continuous ambulatory peritoneal dialysis (CAPD) is cost effective, easy to learn, and requires no complex equipment, thus, is well-suited as a home dialysis modality in areas with distant or limited dialysis facilities. ... -
Effects and mechanisms of interleukin-10 promoter polymorphisms on HIV-1 susceptibility and pathogenesis.
(2012)HIV infection has risen to pandemic proportions. Interleukin-10 (IL-10), a potent antiinflammatory cytokine has been shown to enhance the establishment and persistence of chronic viral infections through inactivation of ... -
The influence of helminths on immune responses to HIV.
(2009)In South Africa, co-infection with HIV and intestinal parasites is a major challenge in disadvantaged communities who live in densely populated under-serviced urban informal settlements. This pilot cross sectional study ... -
Human lymphocyte antigens.
(1992)This thesis embodies much of my work done over the past 25 years. The impetus for these studies was the need to provide the best tissue typing available for organ transplantation and to overcome the problems of defining ... -
Cardiovascular evaluation of hypertensive disorders of pregnancy by echocardiography.
(2004)Background: Preliminary observations suggest that aberrations in maternal central hemodynamics and uterine artery Doppler velocimetry reflect the severity of hypertensive disorders of pregnancy. In addition, the precise ...