Browsing Masters Degrees (Physiology) by Title
Now showing items 41-55 of 55
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An investigation into the apoptotic inducing effect of fusaric acid on human lymphocytes and its role in cell growth inhibition.
(2003)Fusaric acid (FA) (5-butylpicolinic acid) is a divalent ion chelating agent that has low affinity for Ca2+ and Mg2+ and a high affinity for other essential metal ions such as Fe2+ Mn2+, Zn2+ and Cu2+. Its mode of action ... -
An investigation into the chemopreventive properties of an indigenous herb, Amaranthus lividus, using cancerous cell lines.
(2005)Chemoprevention may be defined as the inhibition, delay or reversal of carcinogenesis by dietary compounds or their derivatives. "Imifino" is a collective name for many wild plants used predominantly by rural people as ... -
The kind of society required for human flourishing : a critical comparison of the formation of ethical character in Aristotelian and African ethics.
(2005)One thing that ethics attempts to determine is the right way to live in order to attain human flourishing. Both Aristotelian and African ethics give us communitarian accounts of how flourishing is attained by individuals ... -
Mycotoxins in food with particular reference to fumonisin B1 : their health impact on a Kranskop rural community, KwaZulu Natal.
(1998)The use of the multi-mycotoxin screen based on dialysis to analyze foods and feeds for mycotoxins, is well documented. This study investigated the possibility of incorporating FB I into the screen. Maize meal (25g) was ... -
The occurrence and detection of aflatoxin-macromolecular conjugates in humans.
(1998)Aflatoxin Bi (AFBi), a highly toxic fungal metabolite (mycotoxin) of certain strains of Aspergillus, has long been known to be carcinogenic in animal species. Accumulation of epidemiological evidence led to its classification, ... -
The optimisation of a preeclampsia-like L-NAME rat model : a focus on utero-placental dysfunction.
(2014)Preeclampsia is a multi-system pregnancy syndrome characterized by the sudden onset of hypertension, escalated proteinuria and in some cases oedema usually after 20 weeks of gestation. Preeclampsia is further categorized ... -
Optimisation of an analytical method for the analysis of folic acid derivatives in biological materials.
(2007)Folic acid is a water-soluble, B-complex vitamin influencing a number of biological processes in humans and particularly important in the prevention of neural tube defects (associated with spinal bifida) in unborn children. ... -
Oxidative stress of tissue in hypertensive rats.
(2006)Oxidative stress, resulting from an antioxidant/free radical imbalance, is considered to be an important etiologic factor in the patho-physiological changes associated with salt sensitive hypertension. An important unresolved ... -
Prenatal stress and febrile seizures effects on the epigenetic mechanisms involved in cognitive function following treatment with Searsia chirindensis.
(2016)Febrile seizures are of growing concern in the health fraternity within the African continent. These seizures predominantly affect children between the ages of 3 months and 5 years of age. Stress during pregnancy may ... -
A quantification of heat load as assessed by indicators of tissue damage in rats.
(1984)Heatstroke is an illness that occurs when body temperature is grossly elevated, causing widespread tissue damage. The extent of tissue damage depends on the level of body temperature elevation and the duration. Despite ... -
Quantitative determination of fumonisin B1 in biological material.
(1999)The mycotoxin, fumonisin B1 is produced by the mould Fusarium moniliforme, a common contaminant of maize and maize products. Small doses (mg/kg) of ingested fumonisin B1 have been shown to cause diseases and even death in ... -
Studies on the isolation of the polymerase genes from the H1N1 influenza A virus.
(1992)Vaccines directed against the influenza virus become ineffective due to continuous mutation. An alternative approach might be to control replication at the genomic level by enzymatic methylation of the polymerase genes. ... -
Tat protein induced neurocognitive dysfunction.
(2013)Human immunodeficiency virus type 1 (HIV-1) is a major health threat in South Africa. Studies have shown that HIV affects the central nervous system (CNS), and can initiate a progressive neurodegenerative process culminating ... -
The Use of an enzyme-linked immunosorbent assay (Elisa) for the determination and characterization of antiendotoxin antibodies.
(1994)Recent clinical studies have highlighted the effectiveness of immunotherapy for Gram-negative bacteraemia in humans. Studies in America, undertaken on patients with Gram-negative bacteraemia, have shown that mortality was ... -
A voice-centered relational analysis of the career development narratives of six Black African professionals in KwaZulu-Natal, South Africa.
(2018)Career Psychology and career education is not a new concept in the South African context, it is evident dating back as far as 1943. Literature shows that career guidance was first introduced in White schools and later ...