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Immunohistochemical and ultrastructural evaluation of the pathology and aetiopathogenesis of keloid formation.
(2013)
Introduction
Keloids are formed by the excessive production of scar tissue, which extends beyond the margins
of the original injury, often resulting in lesions of grotesque dimensions.
Keloids present a major dilemma ...
The effects of insulin and Syzygium aromaticum-derived oleanolic acid containing dermal patches on kidney function and renal expression of glucose transporters in streptozotocin-induced diabetic rats.
(2014)
Introduction
The tight glycaemic control required to attenuate chronic complications in type 1 diabetes mellitus
requires multiple daily injections of bolus insulin which have been reported to be associated with
Na+ ...
Syzygium aromaticum-derived triterpenes modulate intestinal glucose handling in streptozotocin-induced diabetic rats.
(2014)
Polyphagia in diabetes mellitus ascribed to elevated plasma ghrelin concentrations is associated
with prolonged postprandial hyperglycaemia due to increased activities of intestinal carbohydrate
hydrolyzing enzymes and ...
Transdermal delivery of insulin and Syzygium aromaticum-derived oleanolic acid by dermal patches in streptozotocin-induced diabetic rats : effects on some selected metabolic parameters.
(2014)
The tight glycaemic control required to attenuate chronic complications in type 1 diabetes
mellitus often requires numerous daily injections of bolus insulin. Typically insulin is
administered by subcutaneous needle ...
The effect of sildenafil citrate and kraussianone-2 on pre-eclampsia-like manifestations in Sprague-Dawley rats.
(2011)
Pre-eclampsia, often described as toxaemia of pregnancy, historically represents one of the most widely investigated conditions relating to human reproduction. To date no firm cure has been found and a clear, well defined ...
Fungal endophytes: isolation, identification and assessment of bioactive potential of their natural products.
(2017)
Fungal endophytes produce a broad variety of bioactive compounds with potential to address
some of the unmet human needs. Medicinal plants have an important role to play in the search for
new strains of endophytes ...
Effects of maslimic acid and related triterpene derivatives on kidney function of male Sprague-Dawley rats.
(2014)
Reports indicate that hyperglycaemia leads to development of kidney complications which result
in sodium retention, decrease in glomerular filtration rate (GFR) and high blood pressure. Various
biochemical processes such ...
Mechanisms of cardiovascular effects of oleanolic acid and related synthetic oleanane derivatives : an experimental study.
(2014)
Introduction
Despite the various conventional treatments that are available to treat hypertension, this disease continues to be globally responsible for approximately 9.4 million deaths each year. The high mortality can ...
The cytotoxic effects, anti-iflammatory, antioxidant, antibacterial, and antidiabetic properties of eight selected South African plants for medicinal purposes.
(2020)
People from the Southern African region have been using the fauna and flora of the region in their homes for millennia to treat all sorts of ailments and complaints with great success. This knowledge transfer was done ...
Evaluating immune activation and cellular determinants of thrombosis in pre-diabetes.
(2018)
Introduction
Platelet dysregulation in pre-diabetes plays a major role in the progression of prothrombotic and pro-inflammatory conditions. Cardiovascular disease (CVD), which may occur at the pre-diabetic stage, are a ...