Browsing Doctoral Degrees (Medical Biochemistry) by Title
Now showing items 7-17 of 17
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Hyperglycaemic-induced regulation of SIRT3 and downstream antioxidant profile.
(2015)Hyperglycaemia increases reactive oxygen species (ROS) production and mitochondrial dysfunction which are involved in metabolic disorders. Sirtuin 3 (SIRT3) is a primary mitochondrial deacetylase that regulates mitochondrial ... -
An in vitro and in vivo evaluation of the immuno and neurotoxicological effects of fusaric acid on altered protein kinase signalling cascades.
(2019)Mycotoxins are naturally occurring toxins produced by moulds which contaminate numerous crops and foodstuffs including cereals, nuts and fruits. When consumed, mycotoxins pose a serious threat to both human and animal ... -
An investigation into the biochemical, molecular and epigenetic effects of fumonisin B1 in liver (HEPG2) cells.
(2014)Fumonisins are carcinogenic mycotoxins that occur world wide in maize and maizebased products intended for human consumption. Consumption of fumonisincontaminated maize as a staple diet has been associated with oesophageal ... -
An investigation into the clinical, biochemical, immunological and epigenetic factors in black South Africa women with preeclampsia and HIV.
(2015)Introduction: Preeclampsia (PE) and HIV/AIDS contribute significantly to adverse maternal and perinatal outcomes globally. The treatment of PE remains empiric, however in HIV infection, highly active antiretroviral therapy ... -
An investigation into the TB/HIV manipulation of the T-cell immune response.
(2015)Abstract available in PDF file. -
An investigation of stress-responses in pregnant women exposed to ambient air pollution in Durban, South Africa.
(2017)Living or working within an unhealthy environment is attributed to 12.6 million deaths worldwide and 2.2 million deaths in Africa. Ambient air pollution (AAP) exposure is amongst the major contributors of environmental and ... -
An investigation of the anti-hyperglycaemic, biochemical and molecular effects of 4-hydroxyisoleucine and fenugreek seed extract in comparison to metformin in vitro and in vivo.
(2017)Type two diabetes mellitus (T2D) is a significant cause of premature death and disability, accompanied with negative socio-economic impacts. This metabolic disorder is characterized by hyperglycaemia and defective insulin ... -
Molecular and biochemical aspects of the kallikrein-kinin system in oesophageal carcinoma.
(1999)Abstract available in PDF file. -
Quantification of circulating cell free fetal DNA and cell free total DNA in normal pregnancy and in pregnancy-related hypertension in Black South African Women.
(2016)Abstract available in PDF file. -
Temporal gene expression of Chlamydia trachomatis in keratinocytes at 37° versus 33°C.
(2017)Abstract available in PDF file.