Browsing School of Health Sciences by Title
Now showing items 142-161 of 294
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Grapefruit juice ameliorates nephropathy in streptozotocin induced diabetes.
(2012)Background Diabetic Nephropathy (DN) is the leading cause of end stage renal disease and mortality in diabetic patients. Over the years, medicinal plants have been used to manage diabetes and its complications. Metformin, ... -
The hallmarks of successful alaryngeal voice rehabilitation following a total laryngectomy using tracheo-esophageal puncture with voice prosthesis : perspectives of key role players.
(2012)A total laryngectomy (TL) affects the quality of life (QoL) of individuals who have undergone this surgical procedure, as changes are seen in respiration, swallowing and communication. The aim of this study was to gather ... -
The health and fitness profiles of sport studies students at a tertiary institution in South Africa.
(2014)Introduction The first time most adolescents start to take care of themselves with limited parental support is when they attend university. The watchful guidance of parental support typically wanes and students start ... -
Hypoglycaemic and renal effects of a bioactive plant extract in streptozotocin induced diabetic rats.
(2008)Background: Evidence from our laboratories indicates that triterpene constituents of Syzygium cordatum (Hochst.) [Myrtaceae] crude leaf extracts can be used to treat diabetes mellitus. For the plant derived triterpenes to ... -
Identifying prospective inhibitors against LdtMt5 from Mycobacterium tuberculosis as a potential drug target.
(2018)Tuberculosis (TB) caused by the bacterium, Mycobacterium tuberculosis (M.tb) has resulted in an unprecedented number of deaths over centuries. L,D-transpeptidase enzymes are known to play a crucial role in the biosynthesis ... -
Immunological effects of asymptomatic vibrio cholerae, salmonella enterica serovar typhi and entamoeba histolytica enteric pathogens during HIV infection and exposure.
(2017)Background Asymptomatic infection by enteric pathogens has been attributed to causing several outbreaks in the world. Common pathogens in this category are Vibrio cholerae, Salmonella typhi and Entamoeba histolytica ... -
The impact of a school-based physical activity intervention on learners' health behaviour.
(2014)Introduction: Five percent of South African youth are obese, 20% overweight, 13% stunted and eight percent is underweight. Physical activity among children and adolescents is believed to be insufficient and low levels ... -
Impact of low vision on quality of life of patients with low vision visiting the low vision center of the Eastern Regional Hospital, Ghana.
(2017)Introduction: Low vision impacts quality of life and more so when the vision loss is severe. Persons living with low vision have reduced functionality and psychosocial well-being with the potential for high dependence on ... -
Impact of Pharmacists’ Intervention on the knowledge of HIV infected patients in a public sector hospital of KwaZulu-Natal.
(AOSIS, 2010)Background: The study site started its roll-out of the human immunodeficiency virus (HIV) prevention of mother-to-child transmission in 2006. All patients were counselled by trained counsellors, before seeing a doctor. At ... -
The impact of the introduction of generics and generic references pricing and candesartan and rosuvastatin utilisation, price and expenditure in South Africa.
(2017)Rationale for the study The growth of pharmaceutical expenditure as a percentage of total health care expenditure has stagnated, both locally and globally, despite increasing consumption. Two factors that contributed ... -
In silico investigation of hepatitis c virus: a novel perspective into targeted viral inhibition of NS3 helicase, NS 3/4a protease and NS5b RNA dependent RNA polymerase.
(2019)Hepatitis C Virus (HCV) is an escalating global healthcare and economic burden that requires extensive intervention to alleviate its control. Over the years, drug design efforts have produced many anti-HCV drugs; however, ... -
The in silico investigation of pharmacological targets of the zika virus : insights into the structural characteristics of the NS5 and NS3 proteins from atomistic molecular simulations.
(2017)The re-emerging Zika virus has evolved into a catastrophic epidemic during the past year, with an estimated 1.5 million reported cases of Zika infections worldwide, since the 2015 outbreak in Brazil. The virus has received ... -
The incidence and distribution of ametropia in blacks in Umlazi.
(1988)Age, sex, race, heredity, environment and nutrition have been found to influence ametropia. In this study, the distribution of refractive errors has been investigated in relation to age, sex, race, education and near ... -
The influence of an abductor pollicis longus strengthening program on the symptoms experienced by elderly females presenting with early stage osteoarthritis of the 1st carpo-metacarpal joint : a pilot study for an experimental pre-test/post-test design.
(2014)Introduction: Elderly females are predominantly left impaired by the degenerative impact which osteoarthritis has on the 1st CMC joint. Research supports the successful implementation of early stage conservative management. Aim: ... -
The influence of the application of pharmacokinetics on the effects of theophylline utilisation upon members of the Indian population.
(1989)Theophylline is a dimethylated xanthine similar in structure to caffeine which is commonly found in tea, coffee and cola beverages (Hendeles and Weinberger, 1983; Rall, 1985). Clinically, its most important pharmacological ... -
The injectable contraceptive : user, social and pharmacological perspectives.
(2003)Despite its widespread use, little research has been undertaken on the use of progestogen-only injectable contraceptives by South African women. This thesis is comprised of two sections. Section 1 provides the first ... -
Insight into cancer targets and ligand binding landscape using bioinformatics and integrated molecular modeling tools.
(2017)The alarming rate of varying types of cancer diseases in human remains a global burden requiring drastic treatment in which, a prominent method of combating it is through enzymebased drug design. Metastatic castration-resistant ... -
Integrating human immunodeficiency virus and tuberculosis drug treatment.
(2014)The human immunodeficiency virus (HIV) and tuberculosis (TB) epidemics are major global public health challenges. Worldwide, approximately 42% of TB patients are also co-infected with HIV, and sub-Saharan Africa (SSA) ... -
The integration of multilingualism and culture into augmentative and alternative communication services for school-aged children in KwaZulu-Natal and Gauteng, South Africa.
(2016)Language and cultural diversity influence how individuals of different backgrounds interact. This heterogeneity can affect how Augmentative and Alternative Communication (AAC) services are provided to children with complex ...