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Coreceptor utilization and primary cell tropism by HIV-1 subtype C strains.
Human immunodeficiency virus type 1 (HIV-1) isolates can be differentiated based on their ability to use particular coreceptors – R5 viruses use CCR5, X4 viruses use CXCR4 and R5X4 (dual tropic) viruses use both CCR5 ...
The role of HLA-C restricted CD8+T cell responses in the control of HIV replication.
Certain HLA-B-restricted CD8+ T cell responses are associated with control of viremia whereas HLA-Cw* restricted responses, including Gag epitopes are associated with high viremia. To better understand the role of ...
HIV-1 specific T-Cell responses in chronic HIV infected children during continuous treatment and structured treatment interruptions (STI).
BACKGROUND Sub-Saharan Africa has the highest number of HIV-infected individuals and limited treatment programs. The use of Highly Active Antiretroviral Therapy (HAART) has resulted in a considerable decrease in morbidity ...