Browsing by Author "O'Keefe, Barry."

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Mannose-rich glycosylation patterns on HIV-1 subtype C gp120 and sensitivity to the lectins, Griffithsin, Cyanovirin-N and Scytovirin.

Alexandre, Kabamba B.; Gray, Elin S.; Lambson, Bronwen Elizabeth.; Moore, Penny L.; Choge, Isaac A.; Mlisana, Koleka Patience.; Abdool Karim, Salim Safurdeen.; McMahon, James.; O'Keefe, Barry.; Chikwamba, Rachel.; Morris, Lynn. (Elsevier., 2010)

Griffithsin (GRFT), Cyanovirin-N (CV-N) and Scytovirin (SVN) are lectins that inhibit HIV-1 infection by binding to multiple mannose-rich glycans on the HIV-1 envelope glycoproteins (Env). Here we show that these lectins ...