Now showing items 1-3 of 3

    • Association of HIV-Specific and Total CD8+ T Memory Phenotypes in Subtype C HIV-1 Infection with Viral Set Point. 

      Burgers, Wendy A.; Riou, Catherine.; Mlotshwa, Mandla.; Maenetje, Pholo.; de Assis Rosa, Debra.; Brenchley, Jason.; Mlisana, Koleka Patience.; Douek, Daniel C.; Koup, Richard.; Roederer, Mario.; De Bruyn, Guy.; Abdool Karim, Salim Safurdeen.; Williamson, Carolyn.; Gray, Clive M. (The American Association of Immunologists, Inc., 2009)
      Understanding early immunological events during HIV-1 infection that may set the course of disease progression is important for identifying correlates of viral control. This study explores the association of differentiation ...
    • Increased memory differentiation is associated with decreased polyfunctionality for HIV but not for CMV-specific CD8+ T cells. 

      Riou, Catherine.; Treurnicht, Florette K.; Abrahams, Melissa-Rose.; Mlisana, Koleka Patience.; Liu, Michael K. P.; Goonetilleke, Nilu.; Koup, Richard.; Roederer, Mario.; Abdool Karim, Salim Safurdeen.; De Bruyn, Guy.; Williamson, Carolyn.; Gray, Clive M.; Burgers, Wendy A. (American Association of Immunologists., 2012-09-15)
      The generation of polyfunctional CD8+ T cells, in response to vaccination or natural infection, has been associated with improved protective immunity. However, it is unclear whether the maintenance of polyfunctionality is ...
    • Plasma cytokine levels during acute HIV-1 infection predict HIV disease progression. 

      Roberts, Lindi.; Williamson, Carolyn.; Little, Francesca.; Bebell, Lisa M.; Mlisana, Koleka Patience.; Burgers, Wendy A.; Passmore, Jo-Ann.; Van Loggerenberg, Francois.; Walzl, Gerhard.; Djoba Siawaya, Joel F.; Abdool Karim, Salim Safurdeen.; Abdool Karim, Quarraisha. (Lippincott Williams & Wilkins., 2010)
      Background: Both T-cell activation during early HIV-1 infection and soluble markers of immune activation during chronic infection are predictive of HIV disease progression. Although the acute phase of HIV infection is ...