Now showing items 1-2 of 2

    • The development of CD4 binding site antibodies during HIV-1 infection. 

      Lynch, Rebecca M.; Tran, Lillian.; Louder, Mark K.; Schmidt, Stefan D.; Cohen, Myron.; DerSimonian, Rebecca.; Euler, Zelda.; Gray, Elin S.; Abdool Karim, Salim Safurdeen.; Kirchherr, Jennifer.; Montefiori, David C.; Sibeko, Sengeziwe.; Soderberg, Kelly.; Tomaras, Georgia D.; Yang, Zhi-Yong.; Nabel, Gary J.; Schuitemaker, Hanneke.; Morris, Lynn.; Haynes, Barton F.; Mascola, John R. (American Society for Microbiology., 2012-07)
      Broadly neutralizing antibodies to the CD4 binding site (CD4bs) of gp120 are generated by some HIV-1-infected individuals, but little is known about the prevalence and evolution of this antibody response during the course ...
    • Viral escape from HIV-1 neutralizing antibodies drives increased plasma neutralization breadth through sequential recognition of multiple epitopes and immunotypes. 

      Wibmer, Constantinos Kurt.; Bhiman, Jinal N.; Gray, Elin S.; Tumba, Nancy L.; Abdool Karim, Salim Safurdeen.; Williamson, Carolyn.; Morris, Lynn.; Moore, Penny L. (Plos., 2013-10-31)
      Identifying the targets of broadly neutralizing antibodies to HIV-1 and understanding how these antibodies develop remain important goals in the quest to rationally develop an HIV-1 vaccine. We previously identified a ...