Now showing items 1-10 of 10

    • Drug concentrations after topical and oral antiretroviral pre-exposure prophylaxis: implications for HIV prevention in women. 

      Abdool Karim, Salim Safurdeen.; Kashuba, Angela D. M.; Werner, Lise.; Abdool Karim, Quarraisha. (Elsevier., 2011)
      No abstract available.
    • Duffy-Null–Associated Low Neutrophil Counts Influence HIV-1 Susceptibility in High-Risk South African Black Women. 

      Ramsuran, Veron.; Kulkarni, Hemant.; He, Weijing.; Mlisana, Koleka.; Wright, Edwina J.; Werner, Lise.; Castiblanco, John.; Dhanda, Rahul.; Le, Tuan.; Dolan, Matthew J.; Guan, Weihua.; Weiss, Robin A.; Clark, Robert A.; Abdool Karim, Salim Safurdeen.; Ahuja, Sunil K.; Ndung'u, Thumbi. (Oxford University Press., 2010)
      Background. The Duffy-null trait and ethnic netropenia are both highly prevalent in Africa. The influence of pre-seroconversion levels of peripheral blood cell counts (PBCs) on the risk of acquiring human immunodeficiency ...
    • Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women. 

      Abdool Karim, Salim Safurdeen.; Abdool Karim, Quarraisha.; Frohlich, Janet A.; Grobler, Anna Christina.; Baxter, Cheryl.; Mansoor, Leila E.; Kharsany, Ayesha B. M.; Sibeko, Sengeziwe.; Mlisana, Koleka.; Omar, Zaheen.; Gengiah, Tanuja N.; Maarschalk, Silvia.; Arulappan, Natasha.; Mlotshwa, Mukelisiwe.; Morris, Lynn.; Taylor, Douglas. (American Association for the Advancement of Science., 2010-09)
      The Centre for the AIDS Program of Research in South Africa (CAPRISA) 004 trial assessed the effectiveness and safety of a 1% vaginal gel formulation of tenofovir, a nucleotide reverse transcriptase inhibitor, for the ...
    • Empowering women in human immunodeficiency virus prevention. 

      Abdool Karim, Quarraisha.; Humphries, Hilton Richard.; Stein, Zena. (Elsevier., 2012-08-01)
      Women comprise one-half of people infected with the human immunodeficiency virus in the world, and about 70% of them live in sub-Saharan Africa. Advancing, untreated HIV disease in women has resulted in substantial declines ...
    • Gender-sensitive reporting in medical research. 

      Heidari, Shirin.; Abdool Karim, Quarraisha.; Auerbach, Judith D.; Buitendijk, Simone E.; Cahn, Pedro.; Curno, Mirjam J.; Hankins, Catherine.; Katabira, Elly.; Kippax, Susan.; Marlink, Richard.; Marsh, Joan.; Marusic, Ana.; Nass, Heidi M.; Montaner, Julio.; Pollitzer, Elizabeth.; Ruiz-Cantero, Maria Teresa.; Sherr, Lorraine.; Sow, Papa Salif.; Squires, Kathleen.; Wainberg, Mark A. (BioMed Central., 2012-03)
      Sex and gender differences influence the health and wellbeing of men and women. Although studies have drawn attention to observed differences between women and men across diseases, remarkably little research has ...
    • Genital tract inflammation during early HIV-infection predicts higher plasma viral load set point in women. 

      Roberts, Lindi.; Passmore, Jo-Ann.; Mlisana, Koleka.; Williamson, Carolyn.; Little, Francesca.; Bebell, Lisa M.; Walzl, Gerhard.; Abrahams, Melissa-Rose.; Woodman, Zenda.; Abdool Karim, Quarraisha.; Abdool Karim, Salim Safurdeen. (Oxford University Press., 2011)
      Background. The biggest challenge in human immunodeficiency virus type 1 (HIV-1) prevention in Africa is the high HIV-1 burden in young women. In macaques, proinflammatory cytokine production in the genital tract is necessary ...
    • HIV disease progression in the first year after delivery among african women followed in the HPTN 046 clinical trial. 

      Watts, D. Heather.; Brown, Elizabeth R.; Maldonado, Yvonne.; Herron, Casey.; Chipato, Tsungai.; Reddy, Leanne.; Moodley, Dhayendre.; Nakabiito, Clemensia.; Manji, Karim.; Fawzi, Wafaie.; George, Kathleen.; Richardson, Paul.; Zwerski, Sheryl.; Coovadia, Hoosen Mahomed.; Fowler, Mary Glenn. (Lippincott Williams & Wilkins., 2013-11-01)
      Background: Starting lifelong antiretroviral therapy (ART) in HIV-infected pregnant women may decrease HIV progression and transmission, but adherence after delivery may be difficult, especially for asymptomatic women. We ...
    • Natural killer cell function in women at high risk for HIV acquisition: insights from a microbicide trial. 

      Naranbhai, Vivek.; Altfeld, Marcus.; Abdool Karim, Quarraisha.; Ndung'u, Thumbi.; Abdool Karim, Salim Safurdeen.; Carr, William Henry. (Lippincott Williams & Wilkins., 2012-09-10)
      Objective: To assess the role of natural killer (NK) cells in HIV acquisition. Design: We conducted a nested case–control substudy to the Center for the AIDS Programme of Research in South Africa (CAPRISA004) tenofovir gel ...
    • Time for gender mainstreaming in editorial policies. 

      Heidari, Shirin.; Eckert, Mirjam J.; Kippax, Susan.; Abdool Karim, Quarraisha.; Sow, Papa Salif.; Wainberg, Mark A. (International AIDS Society., 2011)
      The HIV epidemic has been continuously growing among women, and in some parts of the world, HIV-infected women outnumber men. Women’s greater vulnerability to HIV, both biologically and socially, influences their health ...
    • Utility of colposcopy in a phase 2 portion of a microbicide clinical trial of BufferGel and 0.5% PRO 2000 Gel. 

      Chirenje, Zvavahera M.; Masse, Benoit.; Maslankowski, Lisa.; Ramjee, Gita.; Coletti, Anne.; Tembo, Tchangani.; Magure, Tsitsi M.; Soto-Torres, Lydia.; Kelly, Cliff.; Hillier, Sharon L.; Abdool Karim, Salim Safurdeen. (BioMed Central / International AIDS Society., 2012-07-27)
      Background: The majority of new HIV infections are acquired through heterosexual transmission. There is urgent need for prevention methods to compliment behavior change and condom use. Topical microbicide represent a ...