Browsing Caprisa (Centre for the Aids programme of research in South Africa) by Title
Now showing items 340-359 of 448
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A qualitative study of patient motivation to adhere to combination antiretroviral therapy in South Africa.
(Mary Ann Liebert., 2015)Abstract available in pdf. -
Quantitating the multiplicity of infection with human immunodeficiency virus type 1 subtype C reveals a non-poisson distribution of transmitted variants.
(American Society for Microbiology., 2008)Identifying the specific genetic characteristics of successfully transmitted variants may prove central to the development of effective vaccine and microbicide interventions. Although human immunodeficiency virus transmission ... -
A randomized controlled trial of HAART versus HAART and chemotherapy in therapy-naïve patients with HIV-associated Kaposi sarcoma in South Africa.
(Lippincott Williams & Wilkins., 2011)Background: The optimal approach to HIV-associated Kaposi sarcoma (HIV-KS) in sub-Saharan Africa is unknown. With large-scale rollout of highly active antiretroviral therapy (HAART) in South Africa, we hypothesized that ... -
Randomized cross-sectional study to compare HIV-1 specific antibody and cytokine concentrations in female genital secretions obtained by menstrual cup and cervicovaginal lavage.
(Public Library of Science., 2015)Abstract available in pdf. -
Rapid disease progression in HIV-1 subtype C–infected South African women.
(Oxford University Press., 2014)Background. Whereas human immunodeficiency virus (HIV) subtype B–infected individuals generally progress to AIDS within 8–10 years, limited data exist for other clades, especially from Africa. We investigated rates of HIV ... -
Rapid, complex adaption of transmitted HIV-1 full-length genomes in subtype C-infected individuals with differing disease progression.
(Wolters Kluwer Health., 2013)Objective(s): There is limited information on full-length genome sequences and the early evolution of transmitted HIV-1 subtype C viruses, which constitute the majority of viruses spread in Africa. The purpose of this ... -
Ratio of monocytes to lymphocytes in peripheral blood identifies adults at risk of incident tuberculosis among HIV-infected adults initiating antiretroviral therapy.
(Oxford University Press., 2013)Background. Eight decades ago, the ratio of monocytes to lymphocytes (hereafter, the “ML ratio”) was noted to affect outcomes of mycobacterial infection in rabbits. Recent transcriptomic studies support a role for relative ... -
Re-inventing adherence : toward a patient-centered model of care for drug-resistant tuberculosis and HIV.
(International Union against Tuberculosis and Lung Disease., 2016)Abstract available in PDF file. -
Recommendations for the design and use of standard virus panels to assess neutralizing antibody responses elicited by candidate Human Immunodeficiency Virus Type 1 vaccines.
(American Society for Microbiology., 2005)No abstract available. -
Recommendations for the follow-up of study participants with breakthrough HIV infections during HIV/AIDS biomedical prevention studies.
(Wolters Kluwer Health., 2013)Objective: To facilitate collection of cumulative data on longitudinal HIV disease outcomes during HIV prevention studies by developing recommendations for follow-up of the relatively few study participants with breakthrough ... -
Recruitment of high risk women for HIV prevention trials: baseline HIV prevalence and sexual behavior in the CAPRISA 004 tenofovir gel trial.
(Biomed Central, 2010)Background: Young women in sub-Saharan Africa bear a disproportionate burden of HIV infection compared to men but have limited options to reduce their HIV risk. Microbicides could fill an important HIV prevention gap ... -
Recurrent tuberculosis among HIV-coinfected patients: a case series from KwaZulu-Natal.
(Dove Medical Press., 2018)Abstract available in pdf. -
Relationship between levels of inflammatory cytokines in the genital tract and CD4+ cell counts in women with acute HIV-1 infection.
(The Infectious Diseases Society of America., 2008)Inflammatory responses at mucosal surfaces after human immunodeficiency virus type 1 (HIV-1) transmission may influence disease outcome.We evaluated levels of interleukin (IL)–1B , IL-6, tumor necrosis factor– a, IL-8, ... -
A reliable phenotype predictor for human immunodeficiency virus type 1 subtype C based on envelope V3 sequences.
(American Society for Microbiology., 2005)In human immunodeficiency virus type 1 (HIV-1) subtype B infections, the emergence of viruses able to use CXCR4 as a coreceptor is well documented and associated with accelerated CD4 decline and disease progression. However, ... -
Replication capacity of viruses from acute infection drives HIV-1 disease progression.
(American Society for Microbiology., 2017)Abstract available in pdf. -
Research ethics governance in times of Ebola.
(Oxford University Press., 2017)Abstract available in pdf. -
Restoration of CD4+ responses to copathogens in HIV-infected individuals on antiretroviral therapy is dependent on T cell memory phenotype.
(American Association of Immunologists., 2015)Abstract available in pdf. -
Results from the workshop “problem formulation for the use of gene drive in mosquitoes”.
(American Society of Tropical Medicine and Hygiene., 2017)Abstract available in pdf. -
Results of effectiveness trials of PRO 2000 gel: lessons for future microbicide trials.
(Future Medicine., 2010)No abstract available. -
A retrospective cohort study of body mass index and survival in HIV infected patients with and without TB co-infection.
(Springer., 2018)Abstract available in pdf.