Browsing Biochemistry by Title
Now showing items 131-150 of 201
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Neutrophil tissue inhibitor of matrix metalloproteinases-1 (TIMP- 1) : novel localisation, mobilisation and possible role.
(2002)At the beginning of this study, the granule localisation and regulation of release of human neutrophil (PMNL) precursor collagenases, proMMP-8 and -9 (type I and type TV/V collagenases, respectively), enzymes highly ... -
Nickel accumulation and tolerance in Berkheya coddii and its application in phytoremediation.
(1998)As pollution becomes an ever-increasing threat to the global environment pressure is being placed upon industry to "clean-up" its act, both in terms of reducing the possibility of new pollution and cleaning up already ... -
Novel epidermal growth factor directed cationic lipoplexes promote in vitro hepatotropic gene targeting.
(2014)The need for the improvement in protocols for cellular gene delivery has propelled cytofectin based liposomes as suitable non-viral gene carriers. The amenability of cationic liposomes to modification enables research based ... -
A novel in vitro anticancer drug delivery strategy using platinum encapsulated gold nanoparticles.
(2017)Abstract available in PDF file. -
The nutritive value of Italian ryegrass (Lolium multiflorum) selected for high dry matter and nonstructural carbohydrate contents.
(2003)In traditional forage breeding programmes, breeders have spent decades improving the agronomic characteristics of grasses, such as herbage yield, persistence and resistance to diseases, without considering the nutrient ... -
The occurrence of mycotoxins in feedstuffs in Natal and aspects of their metabolism in the rumen.
(1985)The fluorodinitrobenzene (FONB), succinic anhydride (SA), dansyl chloride (DAN), dye-binding lysine (OBL), total lysine (TL), ninhydrin (NIN) and Tetrahymena lysine (TET) methods were compared for their ability to ... -
Over-expression of FLO genes in Saccharomyces cerevisiae BY4742 strains bearing a deletion in genes related to cell wall biogenesis.
(2013)Mannoproteins form the outermost layer of the cell wall in Saccharomyces cerevisiae. These glycoproteins are first synthesized in the endoplasmic reticulum and undergo posttranslational modification before they are transported ... -
Over-expression of FLO11 encoded mannoprotein in Saccharomyces cerevisiae.
(2015)Abstract available in PDF file. -
p38 MAPK and the C2C12 cell cycle : in vitro and in silico investigations.
(2011)The mammalian cell cycle and its points-of-entry are well characterized pathways. These points-of-entry are normally regulated via mitogens and include, amongst others, the ERK, JNK and p38 mitogen-activated protein ... -
Phytochemistry and anti-cancer potential of compounds isolated from Kenyan medicinal plants, Moringa oleifera and Prunus africana.
(2014)Cancer is one of the leading causes of death worldwide and of all the cancer related deaths occurring worldwide, 70% are in low and middle income countries. In Africa, the disease kills more people than HIV, TB and malaria ... -
Plasmodium yoelii acetyl-coa carboxylase : detection and characterisation of the recombinant biotinoyl domain.
(2008)Human malaria, caused by four species of the intracellular protozoan parasite Plasmodium, is a major health and economic burden in the tropics where the disease is endemic. The biotindependent enzyme acetyl-CoA carboxylase ... -
Preparation of chemically modified transferrin proteins and an investigation of their reactions with DNA and other nucleic acids.
(1986)The molecular biology of human genetic disorders is under intensive investigation at present. In those cases where the disorder is clearly defined in terms of altered gene structure, possibilities may exist for the correction ... -
The presentation and interpretation of arrow symbolism in biology diagrams at secondary-level.
(2006)The literature contains conflicting ideas about the effectiveness of diagrams, and their constituent symbolism as teaching and learning tools. In addition, only limited research has been specifically conducted on the ... -
Prevalence of molecular markers associated with chloroquine, sulphadoxine-pyrimethamine and lumefantrine resistance following the deployment of artemether-lumefantrine as first-line treatment for uncomplicated falciparum malaria in Gaza Province, Mozambique.
Antimalarial drug resistance is a major contributing factor to the sustained malaria burden in sub-Saharan Africa. Under extreme drug pressure, drug resistant parasites have a selective fitness advantage over wild-type ... -
Properties of Cathepsin L in relation to a role in invasive cancer.
(1998)Cathepsin L, which has been implicated in many tissue degradative pathologies by virtue of its ability to degrade extracellular matrix components, was isolated by a novel, scaled-up protein purification method and purified ... -
Protease distribution in J774 macrophages
(2007)Cathepsin, matrix metalloproteinase (MMP) enzyme and tissue inhibitor of MMP (TIMP) distribution in J774 mouse macrophages has not been comprehensively studied. The distribution and vesicle regulation, trafficking and ... -
Protein expressions of Acinetobacter sp. isolates LT1A and V2 during hydrocarbon degradation.
(2012)Bacteria of the genus Acinetobacter are known to be involved in the degradation, leaching and removal of various hazardous compounds from the environment. Several studies of Acinetobacter spp. have reported on the genes ... -
Proteinases and extracellular matrix degradation in breast cancer.
(1996)A variety of proteases have been shown to promote the progression of cancer by virtue of their ability to degrade extracellular proteinaceous barriers, such as basement membrane and interstitial stroma. At the outset of ... -
Quantitative imaging of tyrosine kinase-drug interactions in cells.
(2012)Kinases play a crucial role in regulating cellular signaling cascades, making them therapeutic targets for several human diseases. In human cancers, mis-regulation and mutations of kinases such as EGFR (epidermal growth ...