Now showing items 1-4 of 4

    • The development of CD4 binding site antibodies during HIV-1 infection. 

      Lynch, Rebecca M.; Tran, Lillian.; Louder, Mark K.; Schmidt, Stefan D.; Cohen, Myron.; DerSimonian, Rebecca.; Euler, Zelda.; Gray, Elin S.; Abdool Karim, Salim Safurdeen.; Kirchherr, Jennifer.; Montefiori, David C.; Sibeko, Sengeziwe.; Soderberg, Kelly.; Tomaras, Georgia D.; Yang, Zhi-Yong.; Nabel, Gary J.; Schuitemaker, Hanneke.; Morris, Lynn.; Haynes, Barton F.; Mascola, John R. (American Society for Microbiology., 2012-07)
      Broadly neutralizing antibodies to the CD4 binding site (CD4bs) of gp120 are generated by some HIV-1-infected individuals, but little is known about the prevalence and evolution of this antibody response during the course ...
    • Initial B-Cell responses to transmitted human immunodeficiency virus type 1: virion-binding immunoglobulin M (IgM) and IgG antibodies followed by plasma anti-gp41 antibodies with ineffective control of initial viremia. 

      Tomaras, Georgia D.; Yates, Nicole L.; Liu, Pinghuang.; Qin, Li.; Fouda, Genevieve G.; Chavez, Leslie L.; Decamp, Allan C.; Parks, Robert J.; Ashley, Vicki C.; Lucas, Judith T.; Cohen, Myron.; Eron, Joseph.; Hick, Charles B.; Liao, Hua-Xin.; Self, Steven G.; Landucci, Gary.; Forthal, Donald N.; Weinhold, Kent J.; Keele, Brandon F.; Hahn, Beatrice H.; Greenberg, Michael L.; Morris, Lynn.; Abdool Karim, Salim Safurdeen.; Blattner, William A.; Montefiori, David C.; Shaw, George M.; Perelson, Alan S.; Haynes, Barton F. (American Society for Microbiology., 2008)
      A window of opportunity for immune responses to extinguish human immunodeficiency virus type 1 (HIV-1) exists from the moment of transmission through establishment of the latent pool of HIV-1-infected cells. A critical ...
    • Isolation of a human anti-HIV gp41 membrane proximal region neutralizing antibody by antigen-specific single B cell sorting. 

      Morris, Lynn.; Chen, Xi.; Alam, Munir.; Tomaras, Georgia D.; Zhang, Ruijun.; Marshall, Dawn.; Chen, Bing.; Parks, Robert J.; Foulger, Andrew.; Jaeger, Frederick.; Donathan, Michele.; Bilska, Mira.; Gray, Elin S.; Abdool Karim, Salim Safurdeen.; Kepler, Thomas B.; Whitesides, John.; Montefiori, David C.; Moody, M. Anthony.; Liao, Hua-Xin.; Haynes, Barton F. (Plos., 2011)
      Broadly neutralizing antibodies are not commonly produced in HIV-1 infected individuals nor by experimental HIV-1 vaccines. When these antibodies do occur, it is important to be able to isolate and characterize them to ...
    • Isolation of a Monoclonal Antibody That Targets the Alpha-2 Helix of gp120 and Represents the Initial Autologous Neutralizing-Antibody Response in an HIV-1 Subtype C-Infected Individual. 

      Gray, Elin S.; Moody, M. Anthony.; Wibmer, Constantinos Kurt.; Chen, Xi.; Marshall, Dawn.; Amos, Joshua.; Moore, Penny L.; Foulger, Andrew.; Yu, Jae-Sung.; Lambson, Bronwen E.; Abdool Karim, Salim Safurdeen.; Whitesides, John.; Tomaras, Georgia D.; Haynes, Barton F.; Morris, Lynn.; Liao, Hua-Xin. (American Society for Microbiology., 2011-05-12)
      The C3-V4 region is a major target of autologous neutralizing antibodies in HIV-1 subtype C infection. We previously identified a Center for AIDS Program of Research in South Africa (CAPRISA) participant, CAP88, who ...