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Determinants of optimal adherence over time to antiretroviral therapy amongst HIV positive adults in South Africa : a longitudinal study.

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dc.contributor.authorMaqutu, Dikokole.
dc.contributor.authorZewotir, Temesgen Tenaw.
dc.contributor.authorNorth, Delia Elizabeth.
dc.contributor.authorGrobler, Anna Christina.
dc.date.accessioned2013-08-05T09:44:29Z
dc.date.available2013-08-05T09:44:29Z
dc.date.created2011
dc.date.issued2011
dc.description.abstractHighly active antiretroviral therapy (HAART) requires strict adherence to achieve optimal clinical and survival benefits. A study was done to explore the factors affecting HAART adherence among HIV positive adults by reviewing routinely collected patient information in the Centre for the AIDS Programme of Research in South Africa’s (CAPRISA) AIDS Treatment Programme. Records of 688 patients enrolled between 2004 and 2006 were analysed. Patients were considered adherent if they had taken at least 95% of their prescribed drugs. Generalized estimating equations were used to analyse the data. The results showed that HAART adherence increased over time, however, the rate of increase differed by some of the socio-demographic and behavioural characteristics of the patients. For instance, HAART adherence increased in both urban and rural treatment sites over time, but the rate of increase was higher in the rural site. This helped identify sub-populations, such as the urban population, that required ongoing adherence counseling.en
dc.identifier.citationPublished in final edited form as: Maqutu, D., et al. 2011. Determinants of optimal adherence over time to antiretroviral therapy amongst HIV positive adults in South Africa : a longitudinal study. AIDS Behav. 15 (7) pp. 1465–1474.en
dc.identifier.issn1090-7165
dc.identifier.urihttp://dx.doi.org/10.1007/s10461-010-9688-x.en
dc.identifier.urihttp://hdl.handle.net/10413/9401
dc.language.isoenen
dc.publisherSpringer Verlag.en
dc.subjectHighly active antiretroviral therapy.en
dc.subjectHIV infections-Drug therapy.en
dc.subjectPatient compliance.en
dc.subjectLongitudinal method.en
dc.subject.otherDrug adherence.en
dc.subject.otherHAART adherence.en
dc.titleDeterminants of optimal adherence over time to antiretroviral therapy amongst HIV positive adults in South Africa : a longitudinal study.en
dc.typePeer reviewed journal articleen

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