Now showing items 1-10 of 22
Abnormal IgA1 O-glycosylation in a multi-ethnic population of IgA nephropathy patients in KwaZulu-Natal, South Africa.
Background: The pathogenesis of IgA Nephropathy (IgAN) is poorly understood globally and curative therapy currently does not exist. Variable presentation among IgAN patients globally may be indicative of various underlying ...
Metabolic complications of antiretroviral therapy (ART) in a South African black population..
Aims To determine the prevalence and incidence of lipodystrophy (fat distribution [lipoatrophy and lipohypertrophy] and metabolic complications [insulin resistance-dysglycaemia and dyslipidemia]) in HIV-1 infected adult ...
Quantitative susceptibility testing of chlamydia trachomatis against clinically relevant drugs.
Abstract available in PDF file.
Warfarin : time in therapeutic range, a single centre study on patients using warfarin for stroke prevention in non-valvular atrial fibrillation and prosthetic heart valves.
Background: There are various indications for the use of oral anticoagulants. Two common indications are in patients with atrial fibrillation and prosthetic heart valves. The quality of anticoagulation, determined by the ...
A retrospective review of the demographic profile, disease activity, co-existent co-morbid disease and treatment in established rheumatoid arthritis at a tertiary center clinic.
Rheumatoid arthritis (RA) is one of the most common forms of chronic inflammatory arthritis and often results in joint damage, physical disability and premature mortality. The incidence of RA is increasing in developing ...
The clinical manifestations and response to treatment in South Africans with Lupus nephritis.
Systemic lupus erythematosus (SLE) is an uncommon disease which is being recognised with increasing frequency in Africa, including South Africa. It is most common in young women and is associated with a significant morbidity ...
A description of the profile of the patients and outcomes of fiber-optic bronchoscopies, performed at a tertiary care hospital in KwaZulu-Natal, South Africa, from January to December 2011.
Background Tuberculosis (TB), pneumonia and human immunodeficiency virus (HIV) were the three leading causes of natural deaths in South Africa in 2013 and 11.9% of all deaths in KwaZulu Natal were attributed to TB. In ...
A retrospective review of the clinical outcomes in patients admitted to a newly established medical High Care Unit at King Edward VIII Hospital.
Abstract available in PDF file.
“Sowing the seeds” the use of feedback in postgraduate medical education : a key factor in developing and enhancing clinical competence.
Background: The importance of feedback in enhancing clinical competency in the postgraduate medical education arena is well documented. Many definitions of, and models and frameworks for delivering feedback exist. Trainee ...
The prevalence of bacterial vaginosis in KwaZulu-Natal and its association with the vaginal immune response and shedding of HIV and HSV-2.
Introduction: South Africa has a high burden of sexually transmitted infections (STIs) and HIV. The role of Gardnerella vaginalis in the development of BV has been disputed after the recovery of G. vaginalis from healthy ...