Now showing items 1-10 of 37
Co-formulated abacavir-lamivudine-zidovudine for initial treatment of HIV infection and AIDS.
(The Cochrane Collaboration., 2013-03-28)
The primary objective of this review was to evaluate the antiviral efficacy of co-formulated abacavir-lamivudine-zidovudine for initial treatment of HIV infection. The secondary objectives were to evaluate the safety and ...
Bigotry and oppressive laws in Africa drive HIV in men who have sex with men.
No abstract available.
Community-based intervention is necessary for the control of HIV in North-Central Nigeria.
Objectives: To determine factors associated with the observed high prevalence of HIV in North-Central Nigeria. Methods: In a cross-sectional multisite study conducted in 2007, behavioral, medical, and demographic data ...
Survey of ethical dilemmas facing intensivists in South Africa in the admission of patients with HIV infection requiring intensive care.
(Health & Medical Publications Group., 2013-07)
Background. Maturing of the burgeoning HIV epidemic in South Africa has resulted in an increased demand for intensive care. Objectives. To investigate the influence of ethical dilemmas facing South African intensivists on ...
Changes in natural killer cell activation and function during primary HIV-1 infection.
Background. Recent reports suggest that Natural Killer (NK) cells may modulate pathogenesis of primary HIV-1 infection. However, HIV dysregulates NK-cell responses. We dissected this bi-directional relationship to understand ...
Chest radiograph findings and time to culture conversion in patients with multidrug-resistant tuberculosis and HIV in Tugela Ferry, South Africa.
Background: The majority of patients with multidrug-resistant tuberculosis (MDR-TB) in South Africa are co-infected with HIV, but the radiographic features of MDR-TB and their relationship with time to sputum culture ...
Balancing efficiency, equity and feasibility of HIV treatment in South Africa – development of programmatic guidance.
(BioMed Central., 2013-10-09)
South Africa, the country with the largest HIV epidemic worldwide, has been scaling up treatment since 2003 and is rapidly expanding its eligibility criteria. The HIV treatment programme has achieved significant results, ...
Addressing ethical, social, and cultural issues in global health research.
The purpose of this paper is to encourage reflection among the global health research community and the research ethics community about how a wide range of ethical, social, and cultural (ESC) influences on the conduct, ...
Viral escape from HIV-1 neutralizing antibodies drives increased plasma neutralization breadth through sequential recognition of multiple epitopes and immunotypes.
Identifying the targets of broadly neutralizing antibodies to HIV-1 and understanding how these antibodies develop remain important goals in the quest to rationally develop an HIV-1 vaccine. We previously identified a ...
Ratio of monocytes to lymphocytes in peripheral blood identifies adults at risk of incident tuberculosis among HIV-infected adults initiating antiretroviral therapy.
(Oxford University Press., 2013-12-03)
Background. Eight decades ago, the ratio of monocytes to lymphocytes (hereafter, the “ML ratio”) was noted to affect outcomes of mycobacterial infection in rabbits. Recent transcriptomic studies support a role for relative ...