Now showing items 11-20 of 41
Substitution of Moxifloxacin for Isoniazid during intensive phase treatment of Pulmonary Tuberculosis.
(American Thoracic Society., 2009-08-01)
Rationale: Moxifloxacin has potent activity against Mycobacterium tuberculosis in vitro and in a mouse model of antituberculosis (TB) chemotherapy, but data regarding its activity in humans are limited. Objectives: Our ...
Expanding HIV surveillance to include TB patients in resource-limited settings with a generalized epidemic.
(International Union against Tuberculosis and Lung Disease., 2009-12-01)
Screening of antenatal clinic attendees is central to monitoring the human immunodeficiency virus (HIV) epidemic. However, recent evidence suggests that declining fertility rates are affecting the reliability of antenatal ...
A review of progress on HIV, AIDS and Tuberculosis.
As a United Nations member state, South Africa is signatory to the Millennium Declaration and is committed to achieve the Millennium Development Goals (MDGs) and targets for 2015. This chapter provides an overview ...
Pulmonary resection for extensively drug resistant tuberculosis in KwaZulu-Natal, South Africa.
Background—Extensively-drug resistant tuberculosis (XDR-TB) has been reported in 58 countries around the world and has emerged as a major public health challenge. This is the first report to describe pulmonary resection ...
Population pharmacokinetics and pharmacodynamics of Ofloxacin in South African patients with multidrug-resistant tuberculosis.
(American Society for Microbiology., 2012-07)
Despite the important role of fluoroquinolones and the predominant use of ofloxacin for treating multidrug-resistant tuberculosis in South Africa, there are limited data on ofloxacin pharmacokinetics in patients with ...
A community officer’s perspective of a rural hospital in KwaZulu-Natal.
(South African Medical Association / Health & Medical Publications Group., 2012-06)
No abstract available.
Comparing early treatment outcomes of MDR-TB in a decentralised setting with a centralised setting in KwaZulu-Natal, South Africa.
(International Union against Tuberculosis and Lung Disease., 2012-02-16)
Setting—In KwaZulu-Natal, South Africa, a TB and HIV endemic setting, prolonged hospitalisation for the treatment of the growing number of MDR-TB patients is not possible or effective. Objective—We compared early treatment ...
HIV testing and disclosure: a qualitative analysis of TB patients in South Africa.
(Taylor & Francis., 2007-04-13)
In South Africa, more than 60% of TB patients have HIV co-infection. Voluntary counseling and testing (VCT) is critical to effective HIV prevention, and TB facilities are optimal venues for delivery of these services. ...
Evaluation of time to detection of mycobacterium tuberculosis in broth culture as a determinant for end points in treatment trials.
(American Society for Microbiology., 2010)
Development of new treatments for tuberculosis is hampered by the lack of an accurate surrogate end point and the high degree of efficacy of current 6-month regimens. Sputum culture status after 2 months of therapy, a ...
Multidrug-resistant Tuberculous Meningitis in KwaZulu-Natal, South Africa.
(The Infectious Diseases Society of America., 2003)
Multidrug-resistant (MDR) pulmonary tuberculosis (TB) is well described in the literature. Reports of MDR TB meningitis (MDR-TBM), however, are limited to case reports and a single case series. During the period of 1999-2002, ...