Now showing items 11-20 of 193
HIV prevention transformed : the new prevention research agenda.
We have entered a new era in HIV prevention whereby priorities have expanded from biomedical discovery to include implementation, effectiveness, and the effect of combination prevention at the population ...
Microbicides & their implications in HIV prevention.
(MedKnow Publications., 2010-12)
No abstract available.
Symptomatic vaginal discharge is a poor predictor of sexually transmitted infections and genital tract inflammation in high-risk women in South Africa.
(Oxford University Press., 2012-07-01)
Background. Diagnosis and treatment of sexually transmitted infections (STIs) is a public health priority, particularly in regions where the incidence of human immunodeficiency virus (HIV) infection is high. In most ...
The development of CD4 binding site antibodies during HIV-1 infection.
(American Society for Microbiology., 2012-07)
Broadly neutralizing antibodies to the CD4 binding site (CD4bs) of gp120 are generated by some HIV-1-infected individuals, but little is known about the prevalence and evolution of this antibody response during the course ...
A drug evaluation of 1% tenofovir gel and tenofovir disoproxil fumarate tablets for the prevention of HIV infection.
(Informa Healthcare., 2011)
Introduction: More than a million people acquire HIV infection annually. Pre-exposure prophylaxis (PrEP) using antiretrovirals is currently being investigated for HIV prevention. Oral and topical formulations of tenofovir ...
Adaptive changes in HIV-1 subtype C proteins during early infection are driven by changes in HLA-associated immune pressure.
It is unresolved whether recently transmitted human immunodeficiency viruses (HIV) have genetic features that specifically favour their transmissibility. To identify potential “transmission signatures”, we compared 20 ...
Overview of microbicides for the prevention of human immunodeficiency virus.
Human immunodeficiency virus (HIV) prevention tools that women can use and control are urgently needed. Microbicides are chemical products applied to the vagina or rectum to prevent the sexual transmission of HIV. Four ...
Challenging racial stereotyping of AIDS in South Africa with prevalence of HIV in pregnant women.
(South African Medical Association / Health & Medical Publications Group., 2007)
No abstract available.
Changes in natural killer cell activation and function during primary HIV-1 infection.
Background. Recent reports suggest that Natural Killer (NK) cells may modulate pathogenesis of primary HIV-1 infection. However, HIV dysregulates NK-cell responses. We dissected this bi-directional relationship to understand ...
TB treatment outcomes following directly-observed treatment at an urban outpatient specialist TB facility in South Africa.
The treatment of 450 consecutive new patients with pulmonary TB was evaluated to determine outcome following directly-observed treatment. In all,176 (39.1%) patients were cured, 23 (5.1%) completed treatment, 80 (17.8%) ...