Now showing items 1-10 of 41
A review of progress on HIV, AIDS and Tuberculosis.
As a United Nations member state, South Africa is signatory to the Millennium Declaration and is committed to achieve the Millennium Development Goals (MDGs) and targets for 2015. This chapter provides an overview ...
Population pharmacokinetics and pharmacodynamics of Ofloxacin in South African patients with multidrug-resistant tuberculosis.
(American Society for Microbiology., 2012-07)
Despite the important role of fluoroquinolones and the predominant use of ofloxacin for treating multidrug-resistant tuberculosis in South Africa, there are limited data on ofloxacin pharmacokinetics in patients with ...
Comparing early treatment outcomes of MDR-TB in a decentralised setting with a centralised setting in KwaZulu-Natal, South Africa.
(International Union against Tuberculosis and Lung Disease., 2012-02-16)
Setting—In KwaZulu-Natal, South Africa, a TB and HIV endemic setting, prolonged hospitalisation for the treatment of the growing number of MDR-TB patients is not possible or effective. Objective—We compared early treatment ...
HIV testing and disclosure: a qualitative analysis of TB patients in South Africa.
(Taylor & Francis., 2007-04-13)
In South Africa, more than 60% of TB patients have HIV co-infection. Voluntary counseling and testing (VCT) is critical to effective HIV prevention, and TB facilities are optimal venues for delivery of these services. ...
A community officer’s perspective of a rural hospital in KwaZulu-Natal.
(South African Medical Association / Health & Medical Publications Group., 2012-06)
No abstract available.
Evaluation of time to detection of mycobacterium tuberculosis in broth culture as a determinant for end points in treatment trials.
(American Society for Microbiology., 2010)
Development of new treatments for tuberculosis is hampered by the lack of an accurate surrogate end point and the high degree of efficacy of current 6-month regimens. Sputum culture status after 2 months of therapy, a ...
Lessons from a randomised clinical trial for multidrug-resistant tuberculosis.
(International Union against Tuberculosis and Lung Disease., 2012-12-01)
BACKGROUND: The treatment of multidrug-resistant tuberculosis (MDR-TB) is currently based upon expert opinion and findings from case series, rather than upon randomised clinical trials (RCTs). OBJECTIVE: To describe the ...
(Hindawi Publishing Corporation., 2011)
The intersecting HIV and Tuberculosis epidemics in countries with a high disease burden of both infections pose many challenges and opportunities. For patients infected with HIV in high TB burden countries, the diagnosis ...
The immune reconstitution inflammatory syndrome after antiretroviral therapy initiation in patients with tuberculosis: findings from the SAPiT trial.
(American College of Physicians., 2012-09-04)
Background: Concerns about the immune reconstitution inflammatory syndrome (IRIS) remain a barrier to antiretroviral therapy (ART) initiation during antituberculosis treatment in co-infected patients. Objective: To ...
Case series of the long-term psychosocial impact of drug-resistant tuberculosis in HIV-negative medical doctors.
(International Union against Tuberculosis and Lung Disease., 2010-08-01)
BACKGROUND: Health care workers (HCWs) are at greater risk for tuberculosis (TB), including multidrug-resistant TB (MDR-TB), compared to the general population. The psychosocial impact of nosocomial TB on HCWs has received ...