Now showing items 91-100 of 104
South African HIV-1 subtype C transmitted variants with a specific V2 motif show higher dependence on α4β7 for replication.
(BioMed Central., 2015)
Abstract available in pdf.
Killer-cell Immunoglobulin-like Receptor (KIR) gene profiles modify HIV disease course, not HIV acquisition in South African women.
(BioMed Central., 2016)
Abstract available in PDF file.
Assessing the implementation effectiveness and safety of 1% tenofovir gel provision through family planning services in KwaZulu-Natal, South Africa: study protocol for an open-label randomized controlled trial.
(BioMed Central., 2014)
Background: The Centre for the AIDS Programme of Research in South Africa (CAPRISA) 004 trial demonstrated a 39% reduction in HIV infection, with a 54% HIV reduction in women who used tenofovir gel consistently. A confirmatory ...
Co-enrollment in multiple HIV prevention trials - experiences from the CAPRISA 004 Tenofovir gel trial.
Background—In settings where multiple HIV prevention trials are conducted in close proximity, trial participants may attempt to enroll in more than one trial simultaneously. Co-enrollment impacts on participant’s safety ...
Low adverse event rates following voluntary medical male circumcision in a high HIV disease burden public sector prevention programme in South Africa.
(International AIDS Society., 2014)
Introduction: The provision of voluntary medical male circumcision (VMMC) services was piloted in three public sector facilities in a high HIV disease burden, low circumcision rate province in South Africa to inform policy ...
Empowering women in human immunodeficiency virus prevention.
Women comprise one-half of people infected with the human immunodeficiency virus in the world, and about 70% of them live in sub-Saharan Africa. Advancing, untreated HIV disease in women has resulted in substantial declines ...
High rates of tuberculosis in patients accessing HAART in rural South Africa.
(Lippincott Williams & Wilkins., 2014)
Background: The challenge of early tuberculosis (TB) infection among rural patients accessing highly active antiretroviral therapy (HAART) in a resource-limited setting with high HIV and TB burden has not been fully ...
HIV-positive status disclosure in patients in care in rural South Africa: implications for scaling up treatment and prevention interventions.
Abstract available in pdf.
Epidemiological impact of Tenofovir gel on the HIV epidemic in South Africa.
(Lippincott Williams & Wilkins., 2011)
Background: Tenofovir gel, an antiretroviral-based vaginal microbicide, reduced HIV acquisition by 39% in women in a recent randomized controlled clinical trial in South Africa. Methods: To inform policy, we used a dynamical ...
Limited HIV-1 superinfection in seroconverters from the CAPRISA 004 Microbicide trial.
(American Society for Microbiology., 2014)
HIV-1 superinfection (SI) occurs when an infected individual acquires a distinct new viral strain. The rate of superinfection may be reflective of the underlying HIV risk in a population. The Centre for the AIDS Programme ...