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Interleukin-10 Promoter Polymorphisms Influence HIV-1 Susceptibility and Primary HIV-1 Pathogenesis.

Naicker, Dshanta D.; Werner, Lise.; Kormuth, Emil.; Passmore, Jo-Ann.; Mlisana, Koleka Patience.; Abdool Karim, Salim Safurdeen.; Ndung'u, Thumbi. (The Infectious Diseases Society of America., 2009)

Interleukin (IL)–10 directly inhibits human immunodeficiency virus type 1 (HIV-1) replication, but it may also promote viral persistence by inactivation of effector immune mechanisms. Here, we show in an African cohort ...