Now showing items 1-10 of 42
Impact of maternal and infant antiretroviral drug regimens on drug resistance in HIV-infected breastfeeding infants.
(Pediatric Infectious Disease Journal, 2013)
Background: The HIV Prevention Trials Network (HPTN) 046 trial evaluated the efficacy of extended infant nevirapine (NVP) administration for prevention of HIV transmission through breastfeeding. Infants received daily ...
Neutralizing antibody responses in acute human immunodeficiency virus type 1 subtype C infection.
(American society for Microbiology., 2007)
The study of the evolution and specificities of neutralizing antibodies during the course of human immunodeficiency virus type 1 (HIV-1) infection may be important in the discovery of possible targets for vaccine design. ...
Rifampicin mono-resistance in mycobacterium tuberculosis in KwaZulu-Natal, South Africa : A significant phenomenon in a high prevalence TB-HIV region.
(PLoS One, 2013)
Setting: The dual epidemics of HIV-TB including MDR-TB are major contributors to high morbidity and mortality rates in South Africa. Rifampicin (RIF) resistance is regarded as a proxy for MDR-TB. Currently available ...
Recommendations for the follow-up of study participants with breakthrough HIV infections during HIV/AIDS biomedical prevention studies.
(Wolters Kluwer Health., 2013)
Objective: To facilitate collection of cumulative data on longitudinal HIV disease outcomes during HIV prevention studies by developing recommendations for follow-up of the relatively few study participants with breakthrough ...
Development of methods for cross-sectional HIV incidence estimation in a large, community randomized trial.
(PLOS ONE., 2013)
Background: Accurate methods of HIV incidence determination are critically needed to monitor the epidemic and determine the population level impact of prevention trials. One such trial, Project Accept, a Phase III, ...
Antiretroviral drug regimens to prevent mother-to-child transmission of HIV : a review of scientific, program, and policy advances for sub-Saharan Africa.
(Springer Science., 2013)
Considerable advances have been made in the effort to prevent mother-to-child HIV transmission (PMTCT) in sub-Saharan Africa. Clinical trials have demonstrated the efficacy of antiretroviral regimens to interrupt HIV ...
A systematic review of definitions of extreme phenotypes of HIV control and progression.
(Wolters Kluwer Health., 2014)
The study of individuals at opposite ends of the HIV clinical spectrum can provide invaluable insights into HIV biology. Heterogeneity in criteria used to define these individuals can introduce inconsistencies in results ...
High tuberculosis prevalence in a South African prison : the need for routine tuberculosis screening.
(PLoS One., 2014)
Background: Tuberculosis is a major health concern in prisons, particularly where HIV prevalence is high. Our objective was to determine the undiagnosed pulmonary tuberculosis (‘‘undiagnosed tuberculosis’’) prevalence in ...
High rates of tuberculosis in patients accessing HAART in rural South Africa.
(Lippincott Williams & Wilkins., 2014)
Background: The challenge of early tuberculosis (TB) infection among rural patients accessing highly active antiretroviral therapy (HAART) in a resource-limited setting with high HIV and TB burden has not been fully ...
Role of oral candidiasis in TB and HIV co-infection: AIDS Clinical Trial Group Protocol A5253.
(The Union., 2014)
Abstract available in pdf.