Now showing items 61-70 of 121
Effectiveness of early initiation of antiretroviral therapy in adults with HIV associated tuberculosis in Lesotho in 2012.
Background Today Africa is confronted with a huge burden of Human Immunodeficiency Virus (HIV) associated tuberculosis (TB). In 2010, 77% of the TB in Lesotho was HIV associated. The problem is intensified by many ...
TylA has an essential virulence role in mycobacterium tuberculosis pathogenesis.
Mycobacterium tuberculosis (M.tb), the causative agent of the disease tuberculosis, is an ancient pathogen and a major cause of death worldwide. Although various virulence factors of M.tb have been identified, its pathogenesis ...
Genetic and microrna polymorphisms in young South African Indians with coronary artery disease.
The global burden of cardiovascular disease (CVD) is on the increase with coronary artery disease (CAD) estimated to become the leading cause of mortality worldwide by 2020. The age of onset of this chronic disorder is on ...
Improving the efficacy of bacillus calmette guerin vaccine by concomitant inhibition of T regulatory and T helper 2 cells.
Tuberculosis (TB) remains a major threat to human population as currently Mycobacterium tuberculosis (MTB) infects nearly 33% of the global population. Annually, about one and a half million deaths are caused by tuberculosis ...
Hyperglycaemic-induced regulation of SIRT3 and downstream antioxidant profile.
Hyperglycaemia increases reactive oxygen species (ROS) production and mitochondrial dysfunction which are involved in metabolic disorders. Sirtuin 3 (SIRT3) is a primary mitochondrial deacetylase that regulates mitochondrial ...
Protective HLA class I alleles : investigation of viral control and lack of control in chronic HIV-1 subtype C infection.
Abstract available in PDF file.
Assessment of knowledge, attitude, and practice of pregnant women in respect of prevention of Mother-To-Child Transmission (PMTCT) of HIV/AIDS at a selected antenatal clinic in Durban, South Africa.
Background: South Africa is one of the sub-Saharan African countries with high rates of HIV/AIDS infection and Kwazulu-Natal province has a particularly high rate of HIV prevalence. Mother-To-Child Transmission (MTCT) ...
Aortic valve replacement : anatomical considerations in a narrow aortic root.
Coronary artery ostial stenosis is a life threatening complication of aortic valve replacement (AVR) surgery. It occurs in 3-5% of all AVR operations. Most cases occur 1 to 6 months following AVR. However, some cases ...
Exploring knowledge, attitudes and practices among undergraduate female students living in tertiary institution residences in KwaZulu-Natal with regards to the use of contraceptives.
Background: Risky sexual behaviour is a significant part of an undergraduate student life, which can often result in unintended pregnancies, leading to major social and public health concerns. Despite the free availability ...
Factors affecting attendance and participation in group therapy in a private inpatient psychiatric setting.
This study seeks to understand why many patients did not participate in a group therapy programme offered at an inpatient psychiatric hospital in Pietermaritzburg, South Africa. Conducted by an Occupational Therapist, the ...