Now showing items 1-10 of 34
Pharmaceutical availability on newly formulated oral sustained release pellets containing the antihistamine, chlorpheniramine maleate.
The main objective of the present study was to determine the feasibility of obtaining aqueous polymer-coated pellet formulations using EudragitR NE 30 D dispersion and chlorpheniramine maleate as the model drug. Many factors ...
Hypoglycaemic and renal effects of a bioactive plant extract in streptozotocin induced diabetic rats.
Background: Evidence from our laboratories indicates that triterpene constituents of Syzygium cordatum (Hochst.) [Myrtaceae] crude leaf extracts can be used to treat diabetes mellitus. For the plant derived triterpenes to ...
HIV and the metabolic syndrome.
Abstract not available.
Beta-lactamase mediated resistance in Escherichia Coli isolated from state hospitals in KwaZulu-Natal.
Escherichia coli, one of the most common pathogens causing urinary tract infections, has shown increased resistance to commonly used antibiotics. In this study we analyzed the β-lactamase profiles of 38 inhibitor-resistant ...
Grapefruit juice ameliorates nephropathy in streptozotocin induced diabetes.
Background Diabetic Nephropathy (DN) is the leading cause of end stage renal disease and mortality in diabetic patients. Over the years, medicinal plants have been used to manage diabetes and its complications. Metformin, ...
Enhancing the buccal permeability potential of model ARV drugs : permeability and histo-morphological evaluations.
Buccal delivery of antiretroviral (ARV) drugs may overcome disadvantages such as low bioavailability due to extensive first pass effects and gastrointestinal degradation associated with the oral route. However, the small ...
Computational insight into the glycosidase enzyme using bioinformatics tools and molecular dynamic simulations.
One of the subjects focused on by theoretical and computational studies is that of the molecular systems. Molecular dynamic simulations can provide useful insights into the dynamic, thermodynamic and structural properties ...
The toxicological properties of Scilla nervosa (Burch.) Jessop (Hyacinthaceae) in cultured HepG2 liver cells.
Background and Aims of Study. Scilla nervosa is a member of the Hyacinthaceae plant family that has been naturalised in the grasslands of Southern Africa. The bulbs are traditionally used to treat a variety of ailments. ...
Antimicrobial and chemical analyses of selected bulbine species.
The use of plant materials for the treatment of various diseases is very common in African countries. As traditional medicine used by the rural people does not always have a proper scientific basis, research programmes ...