Browsing Masters Degrees (Chemistry) by Advisor "Govender, Thavendran."
Now showing items 1-4 of 4
Design, synthesis and biological screening of potential anticancer Smac peptidomimetics to target XIAP. Abstract available from print copy only.
Traditional chemotherapeutic drugs are often restricted by severe side effects and a lack of specificity. An approach aimed at improving the selectivity of cancer drugs includes the use of prodrugs that can be selectively ...
(2001)Amino acids are important building blocks for the synthesis of a large number of biologically active compounds and drugs. Amino acids with the pentacyclo-undecane (1) and trishomocubane (2) frameworks fall into the class ...
Synthesis of novel tetrahydroisoquinoline chiral ligands for application in asymmetric transfer hydrogenation. (2010)Several tetrahydroisoquinoline (TIQ) diamine derivatives were prepared for use as ligands in asymmetric transfer hydrogenation (ATH) of acetophenone of which 17 intermediates and the eight target ligands were novel compounds. ...