Now showing items 1-10 of 17
Approaches to the total synthesis of a novel diarylheptanoid
The total synthesis of a novel diarylheptanoid isolated from a South African medicinal plant, Siphonochilus aethiopicus, was investigated. S. aethiopicus (Indungulu in Zulu) is the only South African species of the ...
Structure and synthesis of Gunnera perpensa secondary metabolites.
The project focused on the isolation, characterization and synthesis of secondary metabolites of Gunnera perpensa L. (Gunneraceae), a South African medicinal plant used by many South African women to induce or augment ...
Structure and synthesis of Phloroglucinol derivatives from Hypericum roeperianum
The research presented in this study combines natural product chemistry with organic
Structural and synthetic studies of sesquiterpenoids and flavonoids isolated from Helichrysum species
The genus Helichrysum (Asteraceae) consists of approximately 500 species worldwide, with 245 indigenous to South Africa. As a result of the large number of species, the chemistry and biological activity of several species ...
Synthesis of prenylated benzoquinones.
The research presented in this study demonstrates the critical role that organic synthesis plays in natural product chemistry. The biological activity demonstrated by 2-methyl-6-(3-methyl-2- butenyl)benzo-1,4-quinone ...
Extractives from the Hyacinthaceae.
Four species belonging to the Hyacinthaceae family were investigated. The taxonomy of the Hyacinthaceae is currently under review and therefore compounds isolated from these plants could provide valuable chemical evidence ...
The discovery and characterization of antiprotozoal compounds from South African medicinal plants by a HPLC-based activity profiling technique.
A total of 507 plant extracts from 174 South African plant species, selected based on their traditional uses against parasitic diseases, mainly against malaria were screened against Plasmodium falciprum, Trypanosoma ...
Extractives from eucomis montana and agapanthus inapertus.
Two species belonging to different families were investigated, Eucomis montana from the Hyacinthaceae and Agapanthus inapertus from the Agapanthaceae. To date no previous chemical investigation on Eucomis montana has ...
Bioactive sesquiterpenoids from dicoma anomala subsp. gerrardii
Through South Africa’s first collaborative project between a large scientific organisation, the Council for Scientific and Indust rial Research (CSIR), and the Traditional Healer’s Committee, Dicoma anomala was identified ...
Isolation and characterization of cytotxic compounds from Anthosperum hispidulum and Eriocephalus tenuifolius.
Cancer is a human tragedy that strikes and kills the lives of our beloved people. With a limited number of effective anticancer drugs from natural resources currently in use, there is a real need for new, safe, cheap and ...