Show simple item record

dc.contributor.advisorKruger, Hendrik Gert.
dc.contributor.advisorMaguire, Glen Eamonn Mitchel.
dc.creatorBoyle, Grant Alexander.
dc.date.accessioned2017-02-07T09:13:29Z
dc.date.available2017-02-07T09:13:29Z
dc.date.created2006
dc.date.issued2006
dc.identifier.urihttp://hdl.handle.net/10413/14043
dc.descriptionMaster of Science in Chemistry. University of KwaZulu-Natal, Durban 2006.en_US
dc.description.abstractChiral crown ethers have recently been shown to be useful asymmetric catalysts in many carbon-carbon bond forming reactions. The design and synthesis of new chiral macrocycles and ligands for use in asymmetric catalysis is of great interest in the field of synthetic chemistry. Catalytic asymmetric Michael additions have been studied using chiral crown ethers as phase transfer catalysts. Many chiral crown ethers have been synthesised and tested in asymmetric catalysis but the design of these systems is still an area of much interest. The attempted synthesis of a new class of novel macrocycles such as 1 is described (chapter 2). The synthesis of a new class of chiral cage annulated macrocycles such as 2 is reported (chapter 3). The testing of these macrocycles as catalysts in the Michael addition of 2-nitropropane to chalcone was carried out with poor enantioselectivity being observed Recognition events in chemistry occur on a molecular scale that is difficult to monitor without the use of molecular devices. Photoinduced Electron Transfer (PET) systems have been the subject of much research over the past three decades. The attempted synthesis of the first chiral PET sensor 3 is described (chapter 4).en_US
dc.language.isoen_ZAen_US
dc.subjectMacrocyclic compounds.en_US
dc.subjectParticles (Nuclear physics)--Chirality.en_US
dc.subjectLigands.en_US
dc.subjectTheses--Chemistry.en_US
dc.titleSynthesis of chiral cage annulated macrocycles.en_US
dc.typeThesisen_US
dc.description.notesCould not copy diagrams from abstract.en_US


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record